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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Drug Saf. 2016 Mar;39(3):261–270. doi: 10.1007/s40264-015-0382-9

Table 2.

Proportion of sample use for selected study drugs with the highest projected sample use during the last 5 calendar years of market exclusivity

Rosuvastatin (2009–2013)
Sitagliptin (2009–2013)
Exenatide (2009–2013)
Losartan (2005–2009)
Dabigatran (2010–2013)
New Cont New Cont New Cont New Cont New Cont
Visitsa (n × 1000) 10,937 16,779 3645 4764 905 1077 3064 7471 1217 944
Sample only 8.6 4.7 9.9 3.7 >3.0b >3.0b 12.8 5.8 15.0 10.5
Sample + Rx 39.9 19.3 34.8 13.3 29.1 >3.0b 32.2 12.0 28.5 12.2
Sample any 48.5 23.9 44.7 17.0 38.1 9.8 45.0 17.8 43.5 22.7
Sample days, weighted average 17.8 18.9 17.2 24.5 22.8 25.3 18.6 19.7 13.4 14.7
Insurance type, % sample any
 Private 45.3 20.8 31.1 23.1 >3.0b >3.0b 56.2 9.1 >3.0b >3.0b
 HMO 50.7 24.0 59.2 >3.0b >3.0b >3.0b >3.0b 15.4 >3.0b >3.0b
 PPO 61.7 24.6 48.9 13.0 >3.0b >3.0b 44.2 >3.0b >3.0b <3.0b
 Medicare Part D 41.3 22.6 53.4 15.5 >3.0b >3.0b 58.8 31.7 51.0 23.2
 Medicaid 27.2 26.8 30.0 >3.0b >3.0b >3.0b >3.0b >3.0b >3.0b <3.0b
 No insurance >3.0b >3.0b >3.0b >3.0b <3.0b <3.0b >3.0b >3.0b >3.0b >3.0b
Moxifloxacin, oral (2009–2013)
Moxifloxacin, ophthalmic (2009–2013)
Atomoxetine (2009–2013)
Drospirenone/EE (2008–2012)
Norethindrone/EE/fe (2006–2010)
New Cont New Cont New Cont New Cont New Cont
Visitsa (n × 1000) 12,117 255 11,989 369 1048 2139 6634 12,145 7288 6710
Sample only 10.0 >3.0b 8.2 >3.0b 13.4 >3.0b 16.6 4.7 24.7 17.6
Sample + Rx 14.4 >3.0b 5.8 <3.0b 14.3 10.5 43.3 35.9 56.8 45.1
Sample any 24.3 >3.0b 14.0 >3.0b 27.7 14.4 59.9 40.6 81.5 62.7
Sample days, weighted average 4.8 4.9 5.8 6.8 21.1 15.5 44.6 41.2 47.1 41.9
Insurance type, % sample any
 Private 15.2 >3.0b 17.9 >3.0b 40.0 25.9 61.5 42.7 87.4 73.1
 HMO 17.0 >3.0b 13.7 >3.0b >3.0b >3.0b 56.0 43.8 79.5 57.4
 PPO 32.9 >3.0b 13.8 >3.0b >3.0b >3.0b 62.0 38.4 80.9 59.5
 Medicare part D 35.6 >3.0b >3.0b >3.0b >3.0b >3.0b >3.0b <3.0b >3.0b >3.0b
 Medicaid 14.2 >3.0b 10.0 <3.0b >3.0b >3.0b 63.1 >3.0b 74.3 68.9
 No insurance 55.5 >3.0b 11.9 >3.0b >3.0b >3.0b >3.0b >3.0b 85.4 >3.0b

Data are presented as % unless otherwise indicated. Sample only refers to provision of a sample without accompanying prescription, sample + Rx refers to the provision of a sample together with a prescription for the same drug, and sample any is the sum of sample only and sample + Rx. Data Source: Encuity Research, LLC, TreatmentAnswersTM Audit. Extracted June 2014

Cont continued use, EE ethinyl estradiol, HMO health maintenance organization, PPO preferred provider organization, Rx prescription

a

Visits during which prescription was issued and/or sample was provided for drug of interest

b

Based on fewer than 100,000 projected counts