Table 1.
Baseline characteristics of PEAR African American participants.
| Characteristics* | Atenolol monotherapy (n = 150) |
Metoprolol monotherapy (n = 168) |
Atenolol add- on (n = 141) |
|---|---|---|---|
| Age (mean ± SD) | 47.2 ± 8.5 | 50.0 ± 9.2 | 47.4 ± 8.5 |
| Female gender (n, %) | 107 (71.3%) | 89 (53.0%) | 103 (72.5%) |
| BMI (kg/m2) | 31.6 ± 6.3 | 30.8 ± 5.2 | 31.8 ± 6.2 |
| Duration of hypertension (years) | 6.4 ± 6.8 | 6.8 ± 5.5 | 6.5 ± 6.7 |
| Taking at least 1 antihypertensive drug at entry | 105 (70.0%) | 122 (72.6%) | 100 (70.4%) |
| Smoker (ever) | 52 (34.1%) | 70 (41.7%) | 18 (13%) |
| Baseline office blood pressure | |||
| Systolic (mmHg) | 151.3 ± 12.1 | 150.8 ± 13.2 | 142.4 ± 16.9 |
| Diastolic (mmHg) | 99.0 ± 5.7 | 98.7 ± 6.1 | 90.8 ± 10.1 |
| Baseline Home Blood pressure |
|||
| Systolic (mmHg) | 145.1 ± 10.5 | 147.5 ± 10.7 | 141.9 ± 12.9 |
| Diastolic (mmHg) | 93.9 ± 6.5 | 95.6 ± 6.1 | 89.5 ± 8.1 |
| Plasm renin activity (ng/ml/h), median (interquartile range) |
0.37 (0.21- 0.73) |
0.41 (0.26- 0.74) |
0.93 (0.42- 2.21) |
*
Numeric characteristics were presented as mean± standard deviation or median and interquartile range if not normally distributed; categorical variables were presented as number and percentages.
Abbreviation: SD: standard deviation; BMI: body mass index.