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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Pediatr Infect Dis J. 2016 Mar;35(3):e85–e88. doi: 10.1097/INF.0000000000000997

Table 3.

Factors associated with cardiac dysfunction among HIV infected children on combination antiretroviral therapy by univariate analysis

Cardiac dysfunction
Total Crude Odds Ratio (95% CI) p-value
Present (39) Absent (246)
Age(yrs)
< 5 3 41 44 1.00
≥ 5 36 205 241 2.1 (0.635,7.40) 0.22
Gender
Female 22 132 154 1.00
Male 17 114 131 0.71 (0.35,1.46) 0.36
Viral Load (copies/ml)
<400 22 172 194 1.00
400–5000 3 12 15 1.4(0.37,5.22) 0.61
>5000 11 8 19 0.96 (0.44,2.08) 0.9
CD4 Count (cells/mm3)
<350 7 22 29 1.00
350–750 9 62 71 0.5(0.32,1.00) 0.16
>750–1000 5 36 41 0.08 (0.137,1.141) 0.19
>1000 12 88 100 0.05 (0.171,1.013) 0.11
History of TB
Yes 10 73 83 1.00
No 29 173 202 1.26(0.56,2.82) 0.56
ART
First line 28 177 205
second line 11 69 80 0.8(0.37,1.86) 0.66
Duration from HIV diagnosis
<5yrs 19 109 128
≥5yrs 20 137 157 0.89 (0.44,1.81) 0.77
Duration of ART
<5yrs 22 144 166 1.00
≥5yrs 17 102 119 0.99 (0.49,2.02) 0.99

CI – confidence interval; TB – Tuberculosis; ART – antiretroviral therapy