Table 7. Sex differences in BACHD motor coordination deterioration.

Two-way ANOVA results testing effects of sex and age on challenge beam step errors. When main or interaction effects were identified, significant sex differences within age, and age differences within sex, were identified post-hoc using the Holm-Sidak method for multiple pairwise comparisons.

3 months	Parameter	Males (n = 8)	Females (n = 8)		6 months	Parameter	Males (n = 8)	Females (n = 8)
Challenge Beam	Beam 1	0.3 ± 0.1	0.1 ± 0.1*		Challenge Beam	Beam 1	0.4 ± 0.1	0.5 ± 0.2##
	Beam 2	0.8 ± 0.5	0.3 ± 0.2			Beam 2	1.36 ± 0.5	1.2 ± 0.5##
	Beam 3	0.5 ± 0.5	0.4 ± 0.2			Beam 3	1.9 ± 0.5#	1.1 ± 0.5#*
	Beam 4	1.9 ± 0.4	1.2 ± 0.6			Beam 4	2.7 ± 0.9	2.2 ± 0.6#
	Time	16.5 ± 3.3	17.2 ± 4.1			Time	13.8 ± 4.9	14.0 ± 3.7
			Sex Effect		Age Effect		Interaction
	Parameter	DF	F	P	F	P	F	P
Challenge Beam	Beam 1	31	3.10	NS	16.87	<0.001	0.117	0.02
	Beam 2		1.56	NS	13.56	<0.001	4.22	NS
	Beam 3		5.89	0.022	27.4	<0.001	3.43	NS
	Beam 4		3.79	NS	9.98	0.004	0.09	NS
	Time		0.06	NS	2.9	NS	0.03	NS

*Sex within Genotype, P < 0.05;

^#Age within Sex, P < 0.01;

^##Age within Sex, P < 0.01.

Reported values are mean ± 95% CI