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. 2016 Feb 12;11(2):e0148638. doi: 10.1371/journal.pone.0148638

Table 3. Risk of MS by anti-periodontopathic bacteria IgG antibody and CRP levels.

Independent variables Presence of MS
Model 1 Model 2 Model 3
Crude OR (95% CI) p Adjusted OR (95% CI) p Adjusted OR (95% CI) p Adjusted OR (95% CI) p
Age (years) 1.1 (1.0–1.1) 0.034 1.1 (1.0–1.1) 0.062 1.0 (0.9–1.1) 0.466 1.0 (0.9–1.1) 0.692
Sex: Female 2.3 (1.1–5.1) 0.032 1.3 (0.4–4.0) 0.631 1.1 (0.3–5.0) 0.942 0.9 (0.2–4.0) 0.871
Body mass index (kg/m2) 2.4 (1.7–3.4) <0.001 2.4 (1.7–3.3) <0.001 2.6 (1.6–4.1) <0.001 3.0 (1.7–5.2) <0.001
Plasma anti-A. a IgG Ab levels (U/mL)
1st tertile 1.0 1.0 1.0
2nd tertile 0.4 (0.1–1.1) 0.080 0.1 (0.0–0.5) 0.009 0.1 (0.0–0.9) 0.040
3rd tertile 0.2 (0.1–0.6) 0.003 0.1 (0.0–0.6) 0.015 0.1 (0.0–0.7) 0.022
Plasma anti-P. I IgG Ab levels (U/mL)
1st tertile 1.0 1.0 1.0
2nd tertile 0.7 (0.3–1.8) 0.506 14.7 (1.3–66.5) 0.030 30.9 (1.7–548.8) 0.019
3rd tertile 3.6 (1.3–10.1) 0.013 1.8 (0.3–11.0) 0.542 2.8 (0.4–21.4) 0.312
Plasma anti-P. g IgG Ab levels (U/mL)
1st tertile 1.0 1.0 1.0
2nd tertile 1.2 (0.5–3.0) 0.649 0.4 (0.1–3.1) 0.410 0.3 (0.0–2.2) 0.210
3rd tertile 1.1 (0.5–2.7) 0.821 0.3 (0.1–2.5) 0.295 0.1 (0.0–1.3) 0.079
Plasma CRP levels (ng/mL)
1st tertile 1.0 1.0 1.0
2nd tertile 3.1 (1.3–7.4) 0.014 1.4 (0.3–7.4) 0.675 0.9 (0.2–5.4) 0.894
3rd tertile 8.8 (3.1–25.5) <0.001 7.7 (1.0–59.4) 0.049 9.4 (1.0–88.2) 0.042
Severe periodontitis: Presence 3.8 (1.8–8.1) 0.001 7.8 (1.1–57.0) 0.044