Table 4. P-values, direction and connectivity of genes that consist of significant gene sets and satisfied p < 0.05 in the Affymetrix and Illumina platforms.
Gene Sets | Genes | Affymetrix | Illumina | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
p-value | Direction | Connectivity | Scaled Connectivity | Clustering Coefficient | p-value | direction | Connectivity | Scaled Connectivity | Clustering Coefficient | ||
Cytokine-cytokine receptor interaction | CXCL10 | 0.004 | Down | 7.339 | 0.484 | 0.217 | 0.038 | up | 58.222 | 0.932 | 0.460 |
CXCL6 | 0.009 | Down | 4.709 | 0.311 | 0.139 | 0.028 | up | 57.983 | 0.928 | 0.459 | |
IL12RB2 | 0.013 | Up | 1.703 | 0.112 | 0.053 | 0.030 | up | 57.588 | 0.922 | 0.475 | |
CXCL1 | 0.014 | up | 2.619 | 0.173 | 0.082 | 0.011 | up | 60.767 | 0.972 | 0.475 | |
TNFRSF11B | 0.022 | down | 1.641 | 0.108 | 0.040 | 0.009 | up | 61.191 | 0.979 | 0.478 | |
CXCR4 | 0.029 | up | 1.486 | 0.098 | 0.108 | 0.001 | up | 62.369 | 0.998 | 0.483 | |
Valine, leucine and isoleucine degradation | PCCB | 0.000 | up | 0.156 | 0.023 | 0.088 | 0.025 | down | 13.050 | 0.630 | 0.531 |
ACADM | 0.004 | up | 1.076 | 0.162 | 0.091 | 0.013 | up | 14.366 | 0.693 | 0.519 | |
BCKDHB | 0.015 | up | 3.931 | 0.591 | 0.187 | 0.037 | up | 16.723 | 0.807 | 0.560 | |
AOX1 | 0.036 | down | 3.608 | 0.543 | 0.251 | 0.023 | up | 14.370 | 0.694 | 0.551 | |
HMGCS1 | 0.038 | up | 6.083 | 0.915 | 0.261 | 0.005 | up | 16.723 | 0.807 | 0.495 | |
Systemic lupus erythematosus | HIST1H2BD | 0.000 | down | 6.428 | 1.000 | 0.297 | 0.037 | up | 34.910 | 0.862 | 0.491 |
HLA-DMA | 0.001 | up | 1.531 | 0.238 | 0.209 | 0.049 | up | 34.737 | 0.858 | 0.501 | |
HIST2H3A | 0.002 | down | 6.424 | 0.999 | 0.332 | 0.004 | up | 16.371 | 0.404 | 0.376 | |
HIST1H2BC | 0.006 | down | 5.389 | 0.838 | 0.329 | 0.018 | up | 38.786 | 0.958 | 0.523 | |
H2AFJ | 0.013 | down | 5.692 | 0.886 | 0.364 | 0.008 | up | 40.420 | 0.999 | 0.533 | |
SSB | 0.026 | up | 1.982 | 0.308 | 0.092 | 0.025 | down | 37.591 | 0.929 | 0.514 | |
HIST2H2BE | 0.045 | down | 6.190 | 0.963 | 0.314 | 0.000 | up | 39.830 | 0.984 | 0.529 | |
DNA replication | RfC4 | 0.000 | up | 2.324 | 0.435 | 0.142 | 0.030 | down | 19.755 | 0.917 | 0.603 |
RPA1 | 0.002 | up | 4.078 | 0.763 | 0.207 | 0.001 | down | 21.553 | 1.000 | 0.626 | |
MCM4 | 0.005 | up | 2.725 | 0.510 | 0.274 | 0.001 | down | 21.239 | 0.985 | 0.639 | |
MCM5 | 0.007 | up | 2.773 | 0.519 | 0.301 | 0.014 | down | 19.233 | 0.892 | 0.643 | |
MCM2 | 0.009 | up | 3.880 | 0.726 | 0.201 | 0.009 | down | 19.912 | 0.924 | 0.638 | |
FEN1 | 0.022 | up | 3.304 | 0.618 | 0.209 | 0.039 | down | 18.427 | 0.855 | 0.650 | |
RFC5 | 0.029 | up | 5.344 | 1.000 | 0.184 | 0.031 | down | 19.289 | 0.895 | 0.640 |