Table 1. Baseline characteristics of the study population.
| (N) | PPI (207) | H2A (119) | None (366) | p |
|---|---|---|---|---|
| Vintage (PD before 2005)(%) | 64 (31.1) | 87 (73.5) | 255 (69.9) | 0.0005 |
| Age (years) | 58.8 (16.0) | 64.2 (13.7)* | 57.4 (15.7) | 0.0005 |
| Gender (% males) | 63.6 | 55.9 | 59.6 | 0.38 |
| Diabetes (%) | 85 (41.1) | 44 (31.3) | 117 (32.0) | 0.40 |
| Charlson’s score | 4.4 (2.2) | 4.4 (2.2) | 3.6 (1.9)* | 0.0005 |
| Previous atherothrombotic event (%) | 84 (40.6) | 59 (50.0) | 113 (30.9) | 0.0005 |
| Previous congestive heart failure (%) | 54 (26.1) | 36 (30.5) | 49 (13.4) | 0.0005 |
| Modality of PD (% APD) | 67 (32.4) | 57 (48.3)* | 135 (36.9) | 0.016 |
| Previous/Ongoing immunosuppression (%) | 38 (18.4)* | 8 (6.8) | 16 (4.4) | 0.0005 |
| Malnutrition (%) | 25 (12.1) | 17 (14.4)* | 25 (6.8) | 0.009 |
| GFR (mL/m) | 6.7 (4.0)* | 5.5 (3.7) | 5.7 (3.6) | 0.007 |
| Body mass index (Kg/m2) | 25.9 (4.7) | 26.1 (4.7) | 25.8 (4.4) | 0.81 |
| Plasma albumin (g/L) | 35.5 (6.1) | 36.3 (5.3) | 38.1 (5.4)* | 0.0005 |
| Hemoglobin (g/dL) | 10.7 (1.6) | 10.6 (1.6) | 10.3 (1.6) | 0.055 |
| C-reactive protein (mg/dL) | 0.64(0.10, 52.4) | 0.89 (0.10, 19.8) | 0.53 (0.10, 16.7)** | 0.016 |
| D/P 240’ creatinine | 0.67 (0.13) | 0.66 (0.13) | 0.65 (0.14) | 0.39 |
PPI: Proton pump inhibitors; H2A: H2 receptor antagonists; APD: Automated PD; GFR: Glomerular filtration rate
Figures denote mean values (SD) for numerical variables, median (range) for C-reactive protein and n (%) for categorical variables. Comparisons by ANOVA (Scheffé), χ2 distribution and Mann Whitney’s test.
* Significant difference vs any other group.
** Significant difference vs H2A