Table 2. Urea, creatinine, minerals, PTH, FGF23 and vitamin D metabolites in the blood of cats fed a diet with different levels of dicalcium phosphate.
Mean and standard deviation, n = 10 / diet1
| Group (% Ca in DM) | Polynomial contrasts (P-values) | Reference range2 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 0.6 | 0.8 | 1.5 | 1.9 | 2.2 | 2.4 | Lin. | Quadr. | ||
| Urea (mg/dl) | 49.6 ± 5.30 | 44.4 ± 5.14 | 51.5 ± 9.55 | 56.9 ± 7.81 | 39.2 ± 5.24 | 43.9 ± 5.78 | 0.071 | 0.034 | 30.0–68.0 |
| Creatinine (mg/dl) | 1.73 ± 0.20 | 1.50 ± 0.20 | 1.52 ± 0.21 | 1.49 ± 0.21 | 1.54 ± 0.14 | 1.55 ± 0.24 | 0.034 | 0.001 | 0.60–1.80 |
| Ca (mmol/l) | 2.51 ± 0.11 | 2.41 ± 0.10 | 2.39 ± 0.09 | 2.39 ± 0.10 | 2.46 ± 0.09 | 2.53 ± 0.13 | 0.328 | < 0.001 | 2.30–3.00 |
| Phosphate (mmol/l) | 1.35 ± 0.16 | 1.29 ± 0.14 | 1.37 ± 0.18 | 1.33 ± 0.22 | 1.35 ± 0.16 | 1.39 ± 0.20 | 0.313 | 0.393 | 0.80–1.90 |
| Whole PTH (pg/ml) | 7.25 ± 5.14 | 9.70 ± 7.08 | 9.77 ± 5.56 | 5.79 ± 4.04 | 9.34 ± 8.27 | 10.3 ± 5.74 | 0.488 | 0.575 | |
| Intact PTH (pg/ml) | 10.4 ± 7.13 | 9.76 ± 6.24 | 12.5 ± 5.05 | 4.38 ± 2.46 | 7.17 ± 5.97 | 11.7 ± 7.30 | 0.188 | 0.242 | |
| FGF23 (pg/ml) | 101 ± 58.0 | 110 ± 109 | 112 ± 55.2 | 105 ± 44.7 | 109 ± 42.9 | 134 ± 53.9 | 0.452 | 0.693 | |
| 1α,25(OH)2D3 (ng/ml) | 0.56 ± 0.59 | 0.74 ± 0.35 | 0.59 ± 0.19 | 0.67 ± 0.22 | 0.59 ± 0.15 | 0.49 ± 0.15 | 0.628 | 0.341 | |
| 24,25(OH)2D3 (ng/ml) | 27.4 ± 35.1 | 25.9 ± 12.8 | 18.8 ± 9.84 | 15.2 ± 5.83 | 16.8 ± 6.67 | 13.3 ± 7.54 | 0.122 | 0.685 | |
| 25(OH)D2 (ng/ml) | 0.31 ± 0.17 | 0.52 ± 0.29 | 0.28 ± 0.09 | 0.27 ± 0.06 | 0.24 ± 0.08 | 0.26 ± 0.11 | 0.013 | 0.780 | |
| 25(OH)D3 (ng/ml) | 53.4 ± 19.3 | 71.8 ± 26.5 | 57.7 ± 21.9 | 55.1 ± 12.3 | 52.1 ± 8.95 | 48.5 ± 13.0 | 0.033 | 0.063 | |
| Vitamin D3 (ng/ml) | 2.86 ± 3.13 | 7.08 ± 6.64 | 1.26 ± 0.59 | 7.13 ± 5.23 | 2.13 ± 0.93 | 0.50 ± 0.30 | 0.101 | 0.069 | |
1For the group 3.0% Ca: n = 8
2Clinic of Small Animals, Freie Universität Berlin.