Table 2. Phenotypic outcome in adult life.
Twin A | Twin B | ||||
---|---|---|---|---|---|
Hypertensive disorder in pregnancy in history | Yes | No | Yes | No | |
Measurements and lifestyle | |||||
Age, years | 33 | 33 | 44 | 44 | |
Systolic blood pressure, mmHg | 95 | 100 | 110 | 110 | |
Diastolic blood pressure, mmHg | 58 | 70 | 75 | 76 | |
BMI, kg/m2 | 22.6 | 27.7 | 26.9 | 27.7 | |
Waist circumference, cm | 73.5 | 85 | 85.5 | 90 | |
Hip circumference, cm | 104 | 112.5 | 110.5 | 114 | |
Smoking | No | No | No | No | |
Medication | No | Levothyroxine | Ciclesonide Salbutamol Desloratadine Psyllium | DesloratadinePantoprazole Movicol | |
Laboratory results | Ref | ||||
Cholesterol, mmol/l | 3.9 | 3.6 | 5.1 | 5.2 | < 6,5 |
HDL, mmol/l | 1.33 | 1.31 | 1.88 | 1.86 | > 0.9 |
LDL, mmol/l | 2.3 | 2.0 | 2.9 | 3.0 | < 5.0 |
Triglyceride, mmol/l | 0.6 | 0.7 | 0.8 | 0.8 | < 2,0 |
Fasting glucose, mmol/ml | 4.5 | 4.7 | 4.6 | 4.8 | < 6.1 |
HbA1c, mmol/mol | 36 | 33 | 36 | 36 | 23–43 |
eGFR, mL/min/1.73m2 | >90 | >90 | 65 | 71 | >60 |
NT-proBNP, ng/l | 17 | 23 | 21 | 48 | <2201 |
Microalbumine in urine, mg/l | 4.9 | 4.3 | 3.8 | < 2.0 | < 20 |
Echocardiography | |||||
LVEF, percentage, 2D or 3D analysis | 54, 3D | 54.4, 3D | 60, 2D | 60.5, 3D | |
LV mass, grams | 150 | 102.4 | 148.3 | 139.9 | |
Diastolic function | Normal | Normal | Normal | Normal |
Abbreviations: BMI, Body Mass Index; Ref. range: reference range in non-pregnant women; HDL, High Density Lipoproteïne; LDL, Low Density Lipoproteïne; HbA1c, Glycated hemoglobin; eGFR, estimated glomerular filtration rate; NT-proBNP, N-terminal brain natriuretic peptide; LVEF, Left ventricular ejection fraction; 2D/3D, 2/3 dimensional; LV, Left ventricular.