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. 2015 Dec 8;66(2):143–155. doi: 10.1007/s12576-015-0427-y

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Effects of menthol and capsaicin on human transient receptor potential vanilloid 1 (hTRPV1) or human transient receptor potential melastatin (hTRPM8). a Changes in the Fura-2 ratio in response to capsaicin (0.1 µM) application in the presence and absence of menthol (10 mM) in human embryonic kidney (HEK) 293T cells expressing hTRPV1 (n = 40). b Changes in Fura-2 ratio in response to menthol (1 mM) application in the presence and absence of capsaicin (1 mM) in HEK293T cells expressing hTRPM8 (n = 94). Data are shown as the mean ± standard deviation (SD)