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. 2015 Mar 3;87(2):130–137. doi: 10.1136/jnnp-2014-309932

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Relative expression of Tumour necrosis factor-Related Apoptosis Inducing Ligand (TRAIL) α, TRAIL-β and TRAILR-1, on in vitro stimulation with interferon β (IFNβ), before treatment onset. Those patients who will become non-responders (NR) to IFNβ therapy showed higher expression of TRAIL-α mRNA in the three cellular subsets, while those who will become responders (R) showed higher baseline expression of TRAIL-β and TRAILR-1. Expression level is represented as relative expression compared with the reference gene GAPDH, using the ΔΔCt method. Figures show box plots: the horizontal bars are the median and lower and upper edges of the boxes represent the 25–75th centiles. Lines extending from the box are 10th and 90th centiles.