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. 2014 Dec 30;75(2):356–361. doi: 10.1136/annrheumdis-2014-205698

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Relative change in levels of different anticitrullinated protein antibody (ACPA) specificities in patients with early rheumatoid arthritis receiving add-on therapy at 3 months. For each ACPA specificity, only patients testing positive at baseline were included. ***p<0.001, **p<0.01, n.s., not significant, as tested by non-parametric statistics on absolute antibody levels. CCP, cyclic citrullinated peptide; CEP-1, citrullinated α-enolase peptide-1; cVim, citrullinated vimentin peptide; cFib, citrullinated fibrinogen peptide; MTX, methotrexate; DMARD, disease-modifying anti-rheumatic drugs; TNFi, tumour necrosis factor inhibitor.