Table 3. Marginal Modeling (Generalized Estimating Equations Analysis) Analysis) Results for Evaluating the Effect of Treatment on Frequency, Duration and Severity of Migrainez.
| Response Parameters | ba | SE (b)b | P Value | Exp (b)c |
|---|---|---|---|---|
| Frequency | ||||
| Group (intervention/control) | -0.675 | 0.68 | < .001 | 0.509 |
| Gender (female/male) | 0.158 | 0.074 | .034 | 1.171 |
| Type (without aura/with aura) | 0.081 | 0.079 | .311 | 1.084 |
| Marriage (single/married) | -0.019 | 0.084 | .824 | 0.981 |
| Baseline frequency | 0.389 | 0.028 | < .001 | 1.476 |
| Age | 0.002 | 0.008 | .785 | 1.002 |
| Onset | 0.015 | 0.013 | .265 | 1.015 |
| Time | -0.376 | 0.032 | < .001 | 0.687 |
| Duration | ||||
| Group (intervention/control) | -5.70 | 0.72 | < .001 | NA |
| Gender (female/male) | 0.988 | 0.81 | .225 | NA |
| Type (without aura/with aura) | -0.657 | 1.049 | .531 | NA |
| Marriage (single/married) | -0.834 | 0.927 | .368 | NA |
| Baseline duration | 0.127 | 0.029 | < .001 | NA |
| Age | -0.049 | 0.088 | .578 | NA |
| Onset | 0.181 | 0.172 | .293 | NA |
| Time | -2.390 | 0.258 | < .001 | NA |
| Severity | ||||
| Group (intervention/control) | -3.646 | 0.269 | < .001 | NA |
| Gender (female/male) | 0.501 | 0.232 | .031 | NA |
| Type (without aura/with aura) | -0.009 | 0.316 | .978 | NA |
| Marriage (single/married) | 0.024 | 0.315 | .940 | NA |
| Baseline severity | 0.697 | 0.027 | < .001 | NA |
| Age | -0.028 | 0.028 | .309 | NA |
| Onset | 0.056 | 0.057 | .330 | NA |
| Time | -1.144 | 0.091 | < .001 | NA |
zAbbreviation: NA, not available.
aEstimate of the model parameter.
bStandard error of the estimate.
cRate ratio.