Table 2.
The treatment characteristics include: ETRS, drawing of spirals, handwriting, gait instability, HADS, MoCA and hand function subscores (HF16 and HF32) at baseline (B), 2 days after the procedure (2d), 3 months (3m), and the last follow-up (F) ranging from 1 year (1y) to 2 years (2y) and in percent of improvement (%i)
ETRS (B/3m/1y) | Spiral (B/F/%i) | Handwriting (B/F/%i) | Gait instability (B/2d/F) | HADS (B/2d) | MoCA (B/2d) | HF32 (B/2d) | HF16 (B/2d/%i/3m/%i/1y/%i) | HF16 (2d/1y after the second side/%i) | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Group 1 | 1 | 77/–/52 | 4/1/75 | 4/0/100 | 0/0/0 | 14/8 | 29/30 | 32/20 | 16/4/75/8/50/9/44 | 2.5/4/75 | ||
2 | 65/41.5/18 | 4/0.5/87.5 | 3/0.5/83 | 1.5/1.5/2.5 | 10/22 | 29/29 | 31/19 | 16/3/81/4/78/4/75 | 3.5/2/88 | |||
3 | 55/53/56 | 4/3/25 | 4/3/25 | 1/1/0.5 | 5/7 | 25/26 | 29/21 | 13/5/62/13/0/13/0 | –/–/– | |||
4 | 84/61/– | 4/4/0 | 4/3/25 | 3/3/2 | 22/21 | 26/27 | 32/24 | 16/8/50/11/31/–/– | –/–/– | |||
5 | 70/–/– | 4/1/75 | 3/0/100 | 1.5/1.5/– | 16/– | 25/25 | 32/17 | 16/1/94/5/69/–/– | –/–/– | |||
6 | 77/–/– | 4/4/0 | 3.5/3.5/0 | 2/2/– | –/– | 24/26 | 30/24 | 14/9/36/15/0/–/– | –/–/– | |||
7 | 70/68/– | 4/1.5/62.5 | 4/3/25 | 2.5/2.5/3 | 15/9 | 26/29 | 32/23 | 16/7/56/7/56/–/– | –/–/– | |||
Mean | 71.1/55.9/42 | 4/2.1/46.4 | 3.6/1.9/51.2 | 1.6/1.6/1.6 | 13.7/13.4 | 26.3/27.4 | 31.1/21.1 | 15.3/5.3/64.8/9/40.6/8.7/39.6 | 3/3/81.3 | |||
SD± | 9.4/11.4/20.9 | 0/1.5/– | 0.5/1.6/– | 1/1/1.3 | 5.8/7.4 | 2/1.9 | 1.2/2.7 | 1.3/2.9/–/4.1/–/4.5/– | 0.7/1.4/– | |||
Group 2 | 8 | 61/–/– | 2/0/100 | 4/0/100 | 0/0/0 | 7/– | 28/30 | 24/14 | 10/0/100/0/100/0/100 | |||
9 | 49/20/16 | 3/1/66.7 | 4/2.5/38 | 0/0/0 | 3/1 | 28/28 | 17/4 | 13/1/92/4/69/2/85 | ||||
10 | 53/20/22 | 2.5/0/100 | 1/0/100 | 0/0/0 | 3/2 | 28/30 | 18/11 | 7/0/100/0/100/1/86 | ||||
11 | 67/–/37 | 3/0.5/83 | 2.5/0/100 | 0/0/0.5 | 7/5 | 29/29 | 27/3 | 14/1/93/3/79/3/79 | ||||
12 | 61/–/– | 3/0/100 | 2/0/100 | 0/0/0 | 12/– | 30/30 | 25/15 | 12/2/83/0/100/–/– | ||||
13 | 45/–/11 | 2.5/0/100 | 2/0/100 | 0.5/1/0.5 | 8/6 | 29/29 | 17/4 | 7/0/100/0/100/0/100 | ||||
14 | 50/25/11.5 | 3.5/0/100 | 4/1.5/63 | 2/2.5/2 | 22/18 | 20/25 | 21/10 | 12/1/92/1/92/0/100 | ||||
15 | 46/–/– | 4/0/100 | 2/0/100 | 0/0/0 | 17/– | 27/29 | 17/4 | 13/0/100/0/100/–/– | ||||
16 | 38/–/11.5 | 3/0.5/83 | 2.5/0/100 | 0/1/0 | 2/1 | 29/30 | 16.5/4 | 12.5/0/100/1/92/1/92 | ||||
17 | 56/–/– | 4/0/100 | 3/0/100 | 3/2.5/– | 16/– | 25/29 | 28/13 | 16/1/94/1/94/–/– | ||||
18 | 48/12/10 | 3/0/100 | 3/0/100 | 0/0/0 | 6/11 | 28/29 | 20/8 | 12/0/100/0/100/0/100 | ||||
19 | 36/18/– | 3/0/100 | 3/0/100 | 1/1/1 | 16/17 | 27/27 | 12/4 | 5/0/100/0/100/–/– | ||||
20 | 46/23.5/– | 2/1/50 | 2/0/100 | 0/1/0 | 12/6 | 25/27 | 18/11 | 8/1/88/2.5/69/–/– | ||||
21 | 56/–/– | 3/1/67 | 2.5/0/100 | 0/0/0 | –/– | 27/28 | 22/9 | 12/2/83/3.5/71/3.5/71 | ||||
Mean | 50.9/19.8/17 | 3/0.3/89 % | 2.7/0.3/93 % | 0.5/0.6/0.3 | 10.1/7.4 | 27.1/28.6 | 20.2/8.1 | 11/0.6/95 %/1.1/90 %/1.2/90 % | ||||
SD± | 8.8/4.6/9.8 | 0.6/0.4/– | 0.9/0.8/– | 0.9/0.9/0.6 | 6.3/6.5 | 2.5/1.5 | 4.6/4.3 | 3.1/0.7/–/1.5/–/1.4/– |
MoCA scores pre- and post-procedure show no cognition losses. HADS scores show stable toward improved emotional state (higher scores indicating more emotional distress)