Table 2.
Numbers of cases, total controls, and controls with exposure to each substance. These numbers were based on a filtered sample that removed participants not exposed to alcohol, and participants who are less than 25 years of age and have with no dependence to any assessed substances. NA indicates that the substance was not assessed in the study.
| Alcohol | Cigarettes Per Day (CPD) | Cannabis | Cocaine | Opioid | General Substance Dependence |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Datasets | Cases | Total Controls |
Heavy Smokers |
Total Controls |
Exposed Controls |
Cases | Total Controls |
Exposed Controls |
Cases | Total Controls |
Exposed Controls |
Cases | Total Controls |
Exposed Controls |
Cases | Controls |
| BG | 277 | 1278 | 1449 | 4 | 4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 948 | 3 |
| CADD | 93 | 264 | 54 | 109 | 57 | 72 | 285 | 218 | 35 | 306 | 141 | 6 | 351 | 106 | 161 | 72 |
| CATS | 651 | 1032 | NA | NA | NA | 857 | 831 | 765 | 416 | 1272 | 875 | 1259 | 429 | 102 | 1444 | 209 |
| CEDAR-SADS | 179 | 562 | NA | NA | NA | 255 | 486 | 338 | 86 | 655 | 263 | 114 | 627 | 418 | 342 | 399 |
| Cinciripini | NA | NA | 253 | 34 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 253 | 34 |
| COGA | 612 | 410 | 242 | 483 | 140 | 196 | 823 | 475 | 224 | 795 | 204 | 86 | 933 | 193 | 648 | 318 |
| COGEND | 463 | 1529 | 584 | 935 | 923 | 192 | 1808 | 1543 | 132 | 1871 | 560 | 34 | 1970 | 191 | 918 | 734 |
|
Finnish Health 2000 |
417 | 512 | 89 | 463 | 180 | 3 | 1011 | 0 | 0 | 1014 | 0 | 2 | 1012 | 0 | 453 | 283 |
| FSCD | 280 | 230 | 124 | 276 | 58 | 170 | 340 | 213 | 237 | 273 | 55 | 81 | 429 | 100 | 309 | 193 |
| FT12 | 93 | 470 | 198 | 15 | 15 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 251 | 0 |
| GADD | 43 | 110 | 11 | 57 | NA | 45 | 108 | 78 | 9 | 144 | 29 | NA | 153 | 35 | 75 | 20 |
| GESGA | 1333 | 1933 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1280 | 1926 |
| Kreek | 42 | 684 | NA | NA | NA | NA | NA | NA | 82 | 644 | 41 | 528 | 198 | NA | 527 | 198 |
| MCTFR-Parents | 226 | 2504 | NA | NA | NA | 93 | 2637 | 1637 | 37 | 2695 | 452 | 12 | 2722 | 125 | 283 | 2442 |
| NAG-AUS | 359 | 972 | 737 | 594 | 102 | 79 | 1249 | 694 | 5 | 1322 | 74 | 17 | 1310 | 137 | 766 | 507 |
| NAG-FIN | 221 | 513 | 354 | 115 | 115 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 450 | 101 |
| NYS | 65 | 466 | 71 | 135 | 63 | 25 | 508 | 368 | 26 | 507 | 157 | 1 | 532 | 86 | 135 | 125 |
| OYSUP | All participants were under 25 years of age | |||||||||||||||
| PAGES | 64 | 335 | 132 | 83 | 40 | 77 | 320 | 160 | 7 | 391 | 67 | 8 | 390 | 30 | 210 | 61 |
| PiP | NA | NA | 347 | 54 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 332 | 52 |
| ROMA | 18 | 240 | 209 | 7 | 6 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 177 | 4 |
| SMOFAM | NA | NA | 20 | 67 | 34 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 20 | 67 |
| Utah | 112 | 283 | 235 | 60 | 60 | 36 | 359 | 88 | 16 | 379 | 34 | 9 | 386 | 9 | 272 | 35 |
| VA-Twin | NA | NA | 193 | 70 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 186 | 68 |
| Yale-Penn | 799 | 208 | 1094 | 113 | NA | 397 | 566 | 500 | 911 | 259 | 167 | 703 | 478 | 214 | 1208 | 3 |
| Total | 6347 | 14535 | 6396 | 3674 | 1797 | 2497 | 11331 | 7077 | 2223 | 12527 | 3119 | 2860 | 11920 | 1746 | 11648 | 7834 |