Table 4.
Ordinal Logistic Regression Results | |||||||
---|---|---|---|---|---|---|---|
Substance | Cases | Controls | Cochrane’s Q | Q-Pvalue | Odds Ratio | L95%-U95% | OR-Pvalue |
Alcohol | 2031 | 3361 | 8.90 | 0.351 | 0.90 | 0.76–1.06 | 0.218 |
Nicotine | 2718 | 2674 | 7.78 | 0.455 | 0.89 | 0.74–1.07 | 0.216 |
Cannabis | 839 | 4553 | 10.76 | 0.216 | 0.91 | 0.73–1.14 | 0.420 |
Cocaine | 992 | 4085 | 0.86 | 0.990 | 0.92 | 0.69–1.24 | 0.593 |
Opioid | 607 | 4274 | 3.12 | 0.682 | 0.91 | 0.65–1.27 | 0.577 |
Traditional Logistic Regression Results (Dependence as outcome variable) | |||||||
Alcohol | 2051 | 3430 | 10.66 | 0.222 | 0.88 | 0.76–1.02 | 0.974 |
Nicotine | 2066 | 1412 | 8.69 | 0.276 | 0.91 | 0.76–1.08 | 0.267 |
Cannabis | 861 | 3036 | 9.08 | 0.336 | 0.90 | 0.74–1.09 | 0.283 |
Cocaine | 1011 | 899 | 0.85 | 0.997 | 0.91 | 0.70–1.19 | 0.492 |
Opioid | 600 | 577 | 2.31 | 0.679 | 0.91 | 0.67–1.24 | 0.547 |
Substance column shows the tested outcome phenotype. All effects shows are fixed effect estimates. In the traditional logistic regression results, controls were required to be exposed each tested substance, in addition to meeting the previously applied filters for age and exposure to alcohol.