Table 3.

Results from the whole-brain diagnosis × sex analysis of covariance on response to monetary reward (50¢) versus no reward (0¢)^a

					MNI Coordinates
	BA	Side	Cluster Size	Peak T	X	Y	Z
Cocaine Users > Controls
Putamen		R	163	4.3	30	8	7
					27	14	22
Inferior parietal/supramarginal gyrus	2	L	42	3.7	–45	–28	28
					–45	–28	37
Anterior/middle cingulate gyrus	24,32	R,L	73	3.7	6	17	34
					–9	11	31
Calcarine sulcus	18	L	30	3.6	–3	–70	19
Fusiform gyrus/hippocampus	20	L	41	3.5	–33	–7	–23
Controls > Cocaine Users
Lingual gyrus	19	R	32	3.6	24	–85	–8
Middle/posterior cingulate	23	L	45	3.2	–24	–40	40
					–9	–37	34
Males > Females
Middle/posterior cingulate	23,26	R,L	130	3.7	–9	–25	46
					0	–37	22
					–9	–31	37
Parahippocampal gyrus/hippocampus	37	R	26	3.2	24	–37	–8
					30	–34	7
Females > Males
Postcentral gyrus	3,4	L	48	3.6	–51	–13	40
Diagnosis × Sex Interaction
Precentral gyrus	6	R	26	3.5	33	–16	46
Inferior frontal gyrus	44	L	29	3.5	–39	8	25

^aAnalysis of covariance, controlling for age, BDI scores, and reaction times;

Results are reported at P<0.05 cluster-corrected for multiple comparisons (equal to a height threshold of voxel-level P<0.005 uncorrected and a minimum of 26 contiguous voxels);

Abbreviations: BA, Brodmann area; MNI, Montreal Neurological Institute.