Table 3.

Bivariate Correlations between BDNF Levels and Mood and Cognitive Outcome.

		Acute CSF			Acute Serum			Chronic Serum
		Spearman’s r	p value	n	Spearman’s r	p value	n	Spearman’s r	p value	n
6 Months
PHQ-9 Total		0.16	0.334	39	−0.13	0.490	30	−0.20	0.242	37
Cognitive Composites
Overall		0.13	0.405	41	0.17	0.355	30	0.07	0.678	35
Memory		0.11	0.490	42	0.43	0.019	30	0.04	0.803	35
Executive Function		0.01	0.964	42	−0.18	0.332	31	0.13	0.448	36
Attention		−0.09	0.574	44	−0.07	0.712	33	−0.10	0.520	40
Language Fluency		−0.09	0.589	42	0.10	0.599	30	−0.01	0.953	35
Functional Independence Measure
Cognitive Total		−0.24	0.090	53	0.31	0.041	45	0.16	0.271	47
Memory		−0.24	0.080	53	0.35	0.019	45	0.13	0.369	47
Problem Solving		−0.33	0.015	53	0.33	0.029	45	0.11	0.463	47
Social Interaction		−0.22	0.116	53	0.30	0.044	45	0.05	0.738	47
Expression		−0.12	0.390	53	0.34	0.024	45	0.19	0.190	47
Comprehension		−0.06	0.648	53	0.20	0.186	45	0.27	0.068	47
12 Months
PHQ-9 Total		0.10	0.551	37	−0.38	0.044	29	−0.41	0.019	32
Cognitive Composites
Overall		0.05	0.780	32	0.35	0.137	19	0.01	0.996	28
Memory		0.17	0.339	34	0.53	0.005	26	0.11	0.580	28
Executive Function		0.01	0.962	33	−0.15	0.502	22	−0.14	0.478	29
Attention		0.07	0.716	32	−0.13	0.583	19	0.12	0.530	32
Language Fluency		0.10	0.584	34	0.18	0.372	26	0.00	0.984	29
Functional Independence Measure
Cognitive Total		0.00	0.991	47	0.31	0.063	38	0.19	0.271	35
Memory		−0.15	0.327	47	0.38	0.018	38	0.20	0.251	34
Problem Solving		−0.05	0.762	47	0.30	0.068	38	0.04	0.805	34
Social Interaction		−0.02	0.893	47	0.25	0.133	38	0.08	0.672	34
Expression		0.03	0.817	47	0.27	0.098	38	0.07	0.692	34
Comprehension		0.24	0.101	47	0.18	0.282	38	0.32	0.062	34