Table 1.
Measurements of heart morphometric.
| Parameters | Control (—) | OVX 5 | OVX 9 | Treatment I | Treatment II | Treatment III | ANOVA |
|---|---|---|---|---|---|---|---|
| BW (gram) | 236.5 ± 14.2 | 280.8 ± 33.4 | 264.3 ± 20.0 | 237.0 ± 19.9 | 250.8 ± 16.5 | 252.5 ± 34.6 | 0.124∗ |
| LVW (mg) | 501 ± 16.2 | 578.8 ± 54.6# | 547 ± 41.6 | 502.6 ± 25.1 | 519.2 ± 40.3 | 514.5 ± 30.8 | 0.026∗∗ |
| RVW (mg) | 127 ± 15.6 | 136.6 ± 22.0 | 119.7 ± 16.9 | 125.4 ± 24.9 | 121.8 ± 16.9 | 119.3 ± 8.3 | 0.706 |
| AW (mg) | 82.9 ± 3.4 | 88.9 ± 10.0 | 81.5 ± 5.05 | 88.8 ± 2.9 | 84.4 ± 5.5 | 80.3 ± 1.7 | 0.174 |
| LVW/HW ratio | 0.705 | 0.720 | 0.731 | 0.704 | 0.716 | 0.720 | 0.298 |
| HW/BW ratio | 3.01 × 10−3 | 2.87 × 10−3 | 2.85 × 10−3 | 3.03 × 10−3 | 2.90 × 10−3 | 2.85 × 10−3 | 0.757 |
∗Statistical analysis for body weight using Kruskal-Wallis test as post hoc test. ∗∗ p < 0.05 using one-way ANOVA analysis. # p < 0.05 compared with control (—) using Tukey's test as post hoc test.
BW: body weight; LVW: left ventricular weight; RVW: right ventricular weight; AW: atrial weight; OVX 5: 5-week ovariectomy; OVX 9: 9-week ovariectomy; Treatments I, II, and III: 9-week ovariectomy with 500, 1500, and 2500 mg/kgBW ceplukan leaf's methanolic extract, respectively.