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. 2015 Jun 17;2(3):267–270. doi: 10.1002/mdc3.12193

Table 1.

Pertinent clinical features of 6 patients with OPT plus dystonia

Patient Age/Gender History Nystagmus Palate Tremor Dystonia Other Movement Disorders Pharmacotherapy
1 48/F Resection of deep cerebellar mass Torsional and vertical nystagmus on slight left gaze, nystagmus increases with further eccentric left gaze, no nystagmus on straight‐ahead gaze Yes Torticollis (mild), right hand (mild), both feet (moderate) Lip tremor, speech tremor Baclofen, clonazepam, BoTN
2 46/M Hemorrhagic stroke in pons and midbrain owing to unknown etiology Coarse irregular dysconjugate eye oscillatiions in horizontal, and vertical directions Yes Left laterocollis (mild), right torticollis (mild), right hand Head tremor memantine
3 26/M Pliocytic astrocytoma status postradioablation, hemorrhage Horizontal and vertical pendular nystagmus in straight‐ahead and eccentric gaze No Low face dystonia Upper extremity ataxia Leviteracetam (for history of seizure)
4 42/F Infarction of brainstem, left cerebellar hemisphere, superior vermis, left superior cerebellar peduncle, thalamus, and left occipital cortex owing to vertebral artery dissection Irregular, coarse, disconjugate oscillations of both eyes in all three axes, more prominent nystagmus in vertical axis Yes Torticollis (mild), right‐hand dystonia (mild) Both appendicular ataxia, mild head tremor, perioral twiches memantine, gabapentin, clonazepam
5 56/M Pontine stroke Prominent horizontal and mild torsional nystagmus in primary gaze; no change in eccentric gaze, enucleation of the left eye Yes Moderate‐to‐severe torticollis, mild retrocollis, mild shoulder elevation Upper appendicular ataxia BoTN
6 48/M Pontine hemorrhagic stroke after AVM rupture and fall Horizontal, vertical, and torsional coars, irregular, disconjugate nystagmus Yes Moderate‐to‐severe torticollis, mild laterocollis, moderate bilateral hand dystonia, bilateral foot dystonia memantine

AVM, arteriovenous malformation.