Fig. 1. Effects of NM on histopathology of the lung.
Lung sections, prepared 3 d after exposure of rats to NM or control (PBS) were stained with H & E. NM-induced acute structural changes include multifocal inflammatory lesions (*), characterized by accumulation of inflammatory cells in alveolar spaces (arrow), thickened bronchial epithelium (arrow head), perivascular edema (e), hyperproliferation and hypertrophy of goblet cells (g) and fibrin deposits (f). Original magnification, 4× (top panels), 200× (bottom panels). Representative section from 3 – 7 rats/treatment group are shown.
