Table 2.
No. of participants | No. of cases | Person-years | Hazard ratios (95% confidence intervals) |
||||
---|---|---|---|---|---|---|---|
Model 1a | Model 2b | Model 3c | Model 4d | ||||
Fasting glucose categories (mmol/1) | |||||||
<6.1 | 1091 | 52 | 2482 | 1.00 | 1.00 | 1.00 | 1.00 |
6.1–6.9 | 132 | 18 | 310 | 2.76 (1.61–4.73) | 2.42 (1.39–4.22) | 1.55 (0.85–2.85) | 1.00 (0.48–2.07) |
≥7.0 | 40 | 13 | 98 | 5.30 (2.88–9.76) | 3.32 (1.65–6.67) | 1.03 (0.46–2.31) | 0.57 (0.20–1.61) |
P for trend | <.001 | <.001 | 0.31 | 0.52 | |||
Fasting glucose as a continuous variable (one mmol/1 increase) | 1.67 (1.44–1.93) | 1.61 (1.36–1.91) | 1.04 (0.81–1.32) | 0.72 (0.51–0.99) | |||
2-hour glucose categories (mmol/1) | |||||||
7.8–8.6 | 576 | 14 | 1346 | 1.00 | 1.00 | 1.00 | 1.00 |
8.7–11.0 | 581 | 41 | 1296 | 3.49 (1.90–6.40) | 3.44 (1.85–6.39) | 3.35 (1.80–6.25) | 3.31 (1.68–6.53) |
≥11.1 | 106 | 28 | 248 | 12.1 (6.34–23.1) | 9.64 (4.90–19.0) | 8.81 (4.08–19.0) | 8.67 (3.51–21.4) |
P for trend | <.001 | <.001 | <.001 | <.001 | |||
2-hour glucose as a continuous variable (one mmol/1 increase) | 1.68 (1.51–1.87) | 1.63 (1.45–1.84) | 1.61 (1.38–1.87) | 1.79 (1.46–2.18) | |||
HbA1c (%) | |||||||
<5.6 (38 mmol/mol) | 383 | 4 | 796 | 1.00 | 1.00 | 1.00 | 1.00 |
5.6–6.0 (38–42 mmol/mol) | 348 | 19 | 721 | 4.90 (1.66–14.4) | 4.74 (1.60–14.1) | 4.64 (1.56–13.8) | 3.89 (1.30–11.6) |
≥6.1 (43 mmol/mol) | 377 | 43 | 788 | 10.1 (3.60–28.2) | 8.35 (2.95–23.6) | 7.83 (2.75–22.3) | 6.71 (2.35–19.2) |
P for trend | <0.001 | <0.001 | <0.001 | 0.001 | |||
HbA1c as a continuous variable (one unit [%] increase) | 2.22 (1.64–3.01) | 2.11 (1.50–2.97) | 1.86 (1.25–2.77) | 1.61 (1.02–2.40) |
Adjusted for age, prepregnancy BMI, weight gain during pregnancy, current BMI, family history of diabetes, marital status, education, income, smoking status, passive smoking, leisure-time physical activity, alcohol drinking, and intake of energy, saturated fat, and dietary fiber.
Adjusted for age, prepregnancy BMI, weight gain during pregnancy, current BMI, family history of diabetes, marital status, education, income, smoking status, passive smoking, leisure-time physical activity, alcohol drinking, and intake of energy, saturated fat, and dietary fiber, fasting glucose in analyses of 2-hour glucose and HbA1c, and 2-hour glucose in the analysis of fasting glucose.
Adjusted for age, prepregnancy BMI, weight gain during pregnancy, current BMI, family history of diabetes, marital status, education, income, smoking status, passive smoking, leisure-time physical activity, alcohol drinking, and intake of energy, saturated fat, dietary fiber, fasting glucose, 2-hour glucose and HbA1c other than the variable in the analysis.