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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Ind Microbiol Biotechnol. 2015 Nov 2;43(0):371–387. doi: 10.1007/s10295-015-1704-8

Figure 2.

Figure 2

Modular organization of natural product assembly lines. (a) Modular type I PKS organization. Module ‘n’ shows the minimal domains that are required by most PKS modules. Module ‘n+1’ includes a full complement of reductive domains. Typical starter and extender units are shown, along with an example of a polyketide produced by a type I PKS. (b) Modular NRPS organization. Module ‘n’ shows the minimal domains that are required by each NRPS module. Module ‘n+1’ includes additional domains that are often included. Typical starter and extender units are shown, along with an example of a nonribosomal peptide natural product.