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Intracellular methionine metabolism. Chronic alcohol consumption causes SAM deficiency, but enhancement of homocysteine and SAH. MAT: Methionine adenosyl-transferase; SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine; Hcy: Homocysteine; CBS: Cystathionine beta synthase; SAHH: S-adensylmonocysteine hydrolase; MS: Methionine synthase; BHMT: Betaine-homocysteine methyltransferase.
