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. 2016 Feb 15;7(1):59–71. doi: 10.4291/wjgp.v7.i1.59

Table 3.

Level of scientific evidence (Haute Autorité de Santé, High Autority of Health)

I Large randomized controlled trials with undeniable results
II Small randomized controlled trials and uncertain outcomes
III Non-randomized trials with control groups contemporaries
IV Comparative non-randomized groups with historical controls and case-control studies
V No control groups, patient series
Case reports
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