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. 2016 Jan 18;594(4):985–1003. doi: 10.1113/JP271894

Figure 1. Control recordings in large diameter DCN neurons .

Figure 1

A, injecting a hyperpolarizing current step triggers a rebound firing increase in a Weak burst neuron, with statistically defined burst ISIs indicated by a horizontal bar. Bar plots show peak burst frequencies (above baseline firing rates) for Weak and Transient burst neurons following current pulses that approach E Cl (−75 mV). B, a 50 Hz train of evoked inhibitory postsynaptic currents at maximal intensity (red trace) exhibits a characteristic depression over repeated stimuli. The intensity of Purkinje cell axon stimulation was adjusted to ∼60% of maximum and the stimulus train was superimposed (black trace). C, stimulating Purkinje cell synaptic inputs with a 100 Hz (25 pulse) train inhibits a representative Transient burst DCN neuron and elicits a rebound burst. Bar plots indicate the average peak frequency in Transient and Weak burst phenotypes. Statistically defined burst ISIs are indicated by a horizontal bar. Stimulus artefacts in B and C were digitally reduced.