Table 2.
Composition of artificial and human cerebrospinal fluids
| Osmolality | ||||||||
|---|---|---|---|---|---|---|---|---|
| pH | (mosmol kg−1) | Na+ | K+ | Cl− | Ca2+ | Mg2+ | Glucose | |
| hCSF1 | 7.35 | 293 | 149 | 2.8 | 124.9 | 1.17 | 1.12 | 3.72 |
| aCSF1 | 7.42 ± 0.03 | 288 ± 1 | 147.8 ± 0.4 | 2.79 ± 0.02 | 123.4 ± 0.8 | 1.15 ± 0.02 | 1.13 ± 0.01 | 3.7 ± 0.02 |
| hCSF2 | 7.35 | 287 | 146.1 | 2.89 | 122.9 | 1.13 | 1.14 | 3.31 |
| aCSF2 | 7.41 ± 0.02 | 284 ± 1 | 144.6 ± 0.3 | 2.91 ± 0.01 | 122.8 ± 0.21 | 1.11 ± 0.01 | 1.11 ± 0.02 | 3.37 ± 0.04 |
Concentrations of electrolytes and glucose are in mm. hCSF1: CSF pool from normal pressure hydrocephalus (NPH) patients (n = 10 individuals). aCSF1: aCSF designed to match the NPH pool. Measurements were taken from aCSF solutions prepared on experimental day (n = 5). hCSF2: CSF pool from healthy volunteers (n = 10 individuals). aCSF2: aCSF designed to match the healthy CSF pool. Measurements were taken from aCSF solutions prepared on experimental day (n = 3).