Table 1.
Sociodemographic and Clinical Characteristics of 9H and 3HP Patients in an Urban County Jaila
| Characteristic | 9H Cohort (N = 154) n (%) | 3HP Cohort (N = 91) n (%) | P Value |
|---|---|---|---|
| Median age, years (IQR) | 32 (26–42) | 39 (31–47.5) | <.001 |
| Sex | |||
| Male | 151 (98.1) | 87 (95.6) | .43 |
| Race/ethnicity | .10 | ||
| Hispanic ethnicity | 107 (69.5) | 63 (69.2) | |
| Asian, non-Hispanic | 21 (13.6) | 17 (18.7) | |
| White, non-Hispanic | 13 (8.4) | 4 (4.4) | |
| Other, non-Hispanic | 12 (7.8) | 3 (3.3) | |
| Unknown | 1 (0.6) | 4 (4.4) | |
| Body mass indexb | |||
| Median (IQR) | 25.7 (23.8–29.0) | 25.8 (23.5–29.0) | .39 |
| Medical risk factors and habits | N/A | ||
| Hepatitis B | NC | 1 (1.1) | |
| Hepatitis C | NC | 5 (5.5) | |
| Diabetes | NC | 8 (8.8) | |
| HIV positive | NC | 0 (0.0) | |
| Current or past smoker | NC | 39 (43.9) | |
| History of alcoholismc | NC | 33 (36.3) | |
| History of noninjection drug use | NC | 55 (60.4) | |
| History of injection drug use | NC | 4 (4.4) | |
| Any adverse event | N/A | ||
| Hepatotoxicityd | NCe | 1 (1.1) | |
| Dizziness | NC | 4 (4.4) | |
| Fever or chills | NC | 5 (5.5) | |
| Rash/hives | NC | 4 (4.4) | |
| Abdominal pain | NC | 1 (1.1) | |
| Numbness or tingling | NC | 2 (2.2) | |
| Nausea | NC | 3 (3.3) | |
Abbreviations: BMI, body mass index; IQR, interquartile range; NA, not applicable; NC, data not collected; 3HP, 3 months of isoniazid and rifapentine; 9H, 9-month isoniazid.
a Significance was by Pearson χ2 test for sex, Fisher's exact test for race/ethnicity, and Mann–Whitney U test for age and BMI.
b The BMI is the weight in kilograms divided by the square of the height in meters.
c Patient reported consuming more than 2 alcoholic beverages per day before incarceration.
d Liver function tests included aspartate transaminase or alanine transaminase levels >3 times normal range.
e Data were not collected on adverse drug reactions for 9H cohort, but 1 patient did not complete treatment due to hepatotoxicity.