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. 2015 Oct 27;40(2):252–259. doi: 10.1038/ijo.2015.180

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Association between the GRS of 31 BMI-associated variants with changes in weight at different periods of adult life. (a) Association of the GRS with annual weight change and (b) association of the GRS with substantial weight gain in MDCS and GLACIER. The lowermost results (overall) represent the meta-analyses of estimates in relation to annual weight change or substantial weight gain in n=7000 participants of MDCS and GLACIER from baseline to follow-up. MDCS, Malmö Diet and Cancer Study; GLACIER, Gene x Lifestyle interactions and complex traits involved in elevated disease risk.