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. 2015 Dec 21;37(2):166–176. doi: 10.1038/aps.2015.111

Figure 2.

Figure 2

The effect of YY-23 on NMDA and AMPA-induced current. (A) YY-23 (3 μmol/L) inhibited the current induced by NMDA (100 μmol/L with glycine 2 μmol/L) but had little effect on the current induced by AMPA (50 μmol/L) of representative neurons. The inserted long and short horizontal lines represent the presence of YY-23 and NMDA (or AMPA), respectively. (B) The dose-response curve of the inhibitory effect of YY-23 on NMDA-induced current; 5–6 neurons were detected for every concentration. (C) The statistical diagram of the inhibitory effect of 3 μmol/L YY-23 on NMDA or AMPA-induced current. The data are represented as the mean±SEM. n=6 per group. aP>0.05, cP<0.01 vs CON.