Table 1. Demographic characteristics of the participants (means ± standard deviation, (range)).
NC (n = 26) | svMCI (n = 26) | aMCI (n = 26) | |
---|---|---|---|
Gender (M/F) | 11/15 | 11/15 | align="center">11/15 |
Age (years) | 65.4 ± 8.1 (43–79) | 67.0 ± 9.9 (46–79) | 65.7 ± 7.1 (52–79) |
Years of education | 10.3 ± 4.1 (0–17) | 10.3 ± 4.2 (0–18) | 9.8 ± 5.0 (0–21) |
Number of vascular risk factors | 0.9 ± 1.2 (0–4) | 2.0 ± 0.9 (0–4)* | 0.8 ± 0.9 (0–3)+ |
Arterial hypertension, N (%) | 8 (26) | 18 (69)* | 11 (42) |
Diabetes mellitus, N (%) | 7 (27) | 13 (50) | 3 (12)+ |
Hypercholesterolemia, N (%) | 5 (19) | 6 (23) | 6 (23) |
Heart disease, N (%) | 3 (12) | 11 (42)* | 1 (4)+ |
CDR | 0 | 0.5 | 0.5 |
MMSE | 27.9 ± 2.4 (20–30) | 25.9 ± 2.4 (21–30)* | 24.9 ± 3.3 (18–30)* |
CDT | 2.8 ± 0.5 (1–3) | 2.3 ± 0.8 (1–3)* | 2.2 ± 0.8 (0–3)* |
AVLT-immediate recall | 8.9 ± 2.0 (5.0–14.7) | 5.4 ± 2.1 (3.3–9.7)* | 5.7 ± 1.4 (3.0–8.0)* |
AVLT-delayed recall | 9.7 ± 2.6 (5–15) | 5.7 ± 3.3 (0–12)* | 4.8 ± 2.6 (0–10)* |
AVLT-recognition | 11.9 ± 2.2 (7–15) | 9.5 ± 3.3 (4–14)* | 8.4 ± 3.8 (1–14)* |
*,+ANOVA followed by Bonferroni post hoc analysis for continuous variables or the Chi-square test for categorical variables: *p < 0.05 between NC and svMCI or aMCI; +p < 0.05 between svMCI and aMCI. n = number of subjects; NC, normal control group; svMCI, subcortical vascular mild cognitive impairment group; aMCI, amnestic mild cognitive impairment group; CDR, Clinical Dementia Rating; MMSE, Mini Mental Status Examination; CDT, Clock Drawing Test; AVLT, Auditory Verbal Learning Test.