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. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: J Chem Inf Model. 2014 Jan 21;54(2):648–659. doi: 10.1021/ci4004656

Figure 1.

Figure 1

Both Mdm2 (A) and Mdmx (B) interact with the NTD peptide of p53 via the same Phe, Trp and Leu sidechains which fit into three corresponding pockets on the protein. Structural data from PDB structures 1YCR [12] and 3DAB [13].