. 2015 Nov 24;59(3):841–853. doi: 10.1021/acs.jmedchem.5b00752

Table 1. Structural Modifications with Substituents on the Piperazine Ring^a.

graphic file with name jm-2015-00752u_0008.jpg

EC₅₀ ± SEM (n ≥ 3) is from the HCV-Luc infection assay; CC₅₀ ± SEM (n ≥ 3) is from the ATPlite cytotoxicity assay; selectivity index = CC₅₀/ EC₅₀.

Table 1. Structural Modifications with Substituents on the Piperazine Ringa.