. 2015 Dec 30;7(2):192–197. doi: 10.1021/acsmedchemlett.5b00449

Table 3. Functional Activity Data at hTAAR1 and Selectivity vs hα_2a for Compounds 29–32.

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compd	A	hTAAR1 EC₅₀ (nM)	hTAAR1 E_max	sel. ratio
29	CH₂–CH₂–CH₂	27	86%	217
30	CH₂–O–CH₂	360	102%	n.d.
31	CH₂–CH₂–O	9	98%	818
32	bond	67	104%	670

Table 3. Functional Activity Data at hTAAR1 and Selectivity vs hα2a for Compounds 29–32.