Table 4.
A Priori Selected FA, Adjusted for Gender, IQ, BMI, Tobacco Use
Adjusted | ||||
---|---|---|---|---|
B | SE b | 95% CI | P | |
DHA (C22:6w3) | ||||
Intercept | 12.30 | 2.50 | 7.38 17.22 | <.001 |
Status (overall) | .087 | |||
Controls/patients | −1.45 | 0.72 | −2.87 −0.025 | .046 |
Siblings/patients | −0.026 | 0.58 | −1.17 1.12 | .965 |
Siblings/controlsa | 1.42 | 0.70 | 0.05 2.79 | .042 |
DPA (C22:5w3) | ||||
Intercept | 8.40 | 1.00 | 6.44 10.36 | <.001 |
Status (overall) | .002 | |||
Controls/patients | −0.95 | 0.29 | −1.51 −0.38 | .001 |
Siblings/patients | −0.02 | 0.23 | −0.47 0.43 | .930 |
Siblings/controlsa | 0.93 | 0.28 | 0.38 1.47 | .001 |
AA (C20:4w6) Intercept |
76.79 | 5.100 | 66.77 86.80 | <.001 |
Status (overall) | <.001 | |||
Controls/patients | −3.46 | 1.48 | −6.37 −0.56 | .019 |
Siblings/patients | 2.18 | 1.17 | −0.13 4.48 | .064 |
Siblings/controlsa | 5.64 | 1.42 | 2.85 8.44 | <.001 |
LA (C18:2w6) | ||||
Intercept | 74.39 | 5.71 | 63.16 85.62 | <.001 |
Status (overall) | .098 | |||
Controls/patients | −2.62 | 1.64 | −5.85 0.61 | .112 |
Siblings/patients | 0.76 | 1.37 | −1.93 3.45 | .579 |
Siblings/controlsa | 3.38 | 1.58 | 0.28 6.48 | .033 |
NA (C24:1w9) | ||||
Intercept | 15.49 | 1.80 | 11.95 19.03 | <.001 |
Status (overall) | <.001 | |||
Controls/patients | −1.78 | 0.53 | −2.83 −a0.74 | .001 |
Siblings/patients | 0.63 | 0.39 | −0.14 1.41 | .108 |
Siblings/controlsa | 2.42 | 0.51 | 1.41 3.43 | <.001 |
EPA (C20:5w3)b | ||||
Intercept | 0.39 | 0.95 | −0.92 2.69 | .682 |
Status (overall) | .243 | |||
Controls/patients | −0.31 | 0.18 | −0.73 −0.32 | .058 |
Siblings/patients | −0.04 | 0.19 | −0.52 0.23 | .888 |
Siblings/controlsa | 0.28 | 0.18 | −0.92 0.59 | .079 |
aBecause the regression coefficients of the dummy variables based on the dummy variable coding of the regression analyses only resulted in estimates for the differences between controls and patients and siblings and patients, we re-analyzed the data with an alternative dummy variable coding that also enabled us to estimate the adjusted differences between siblings and controls: coding: controls/ patients: 1/0; coding: siblings/patients: 1/0; coding: siblings/controls: 1/0.
bBootstrap results based on 2000 bootstrap samples.