FIG. 5.

SOD3-transduced MSCs effectively reduce neutrophil and dendritic cell recruitment in spleen compared with MSCs. (A) Representative histograms showing infiltrate populations in spleens. (B–E) Absolute cell numbers and (F) IHC staining for T cells, neutrophils (Gr1+), and dendritic cells (CD11C+) in spleen. Data are represented as mean ± SD. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 (control group vs. IMQ-treated group for all cases); *p < 0.05, ***p < 0.001 (IMQ-treated group vs. MSC-treated group for all cases); scale bar, 50 μm. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars