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Anti-runt-related transcription factor 1 (RUNX1) aptamers. (A) Schematic of the secondary structure of a representative aptamer (minimal region for RUNX1 inhibition boxed in red). Adapted from Barton et al. [148]. (B) These proposed secondary structure of the minimal region hairpin (38 nucleotides, boxed in green) thought to mimic the Runt-binding double-stranded DNA element (RDE). Adapted from Fukunaga et al. [149].
