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. 2016 Feb 1;26(1):29–43. doi: 10.1089/nat.2015.0566

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© Estefanía Mondragón et al, 2015; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (<http://creativecommons.org/licenses/by/4.0>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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FIG. 5. — Heat shock RNA-1 (HSR1) mechanism of action. The HSR1-eEF1A complex is proposed to facilitate and stabilize the trimerization of HSF, which binds at the 5′ terminus of HSR1. HSR1-eEF1A complexes are necessary for activation of heat shock transcription factor 1 (HSF1).