Table 2.
Univariate analysis of overall survival (OS) for potential prognostic factors of patients with non-metastatic locally recurrent NPC
Variable | Entire cohort (69 patients) | χ2 | P valuea | CCRT group (34 patients) | RT group (35 patients) | χ2 | P valuea | |||
---|---|---|---|---|---|---|---|---|---|---|
n | 5-year OS rate (%) | n | 5-year OS rate (%) | n | 5-year OS rate (%) | |||||
Sex | 0.810 | 0.368 | ||||||||
Male | 57 | 33.4 | 27 | 37.0 | 30 | 28.9 | 1.941 | 0.164 | ||
Female | 12 | 41.7 | 7 | 57.1 | 5 | 20.0 | 2.849 | 0.091 | ||
Age (years) | 9.656 | 0.002 | ||||||||
≤46 | 38 | 46.3 | 22 | 43.0 | 16 | 50.0 | 0.039 | 0.843 | ||
>46 | 31 | 19.9 | 12 | 38.5 | 19 | 10.5 | 3.385 | 0.066 | ||
rT categoryb | 10.342 | 0.001 | ||||||||
rT1–2 | 15 | 72.2 | 5 | 100 | 10 | 60.0 | 2.725 | 0.099 | ||
rT3–4 | 54 | 24.2 | 29 | 33.0 | 25 | 13.2 | 6.789 | 0.009 | ||
rN categoryb | 0.049 | 0.824 | ||||||||
rN0 | 59 | 33.2 | 30 | 40.1 | 29 | 25.2 | 3.614 | 0.057 | ||
rN1–2 | 10 | 44.4 | 4 | 50.0 | 6 | 40.0 | 0.161 | 0.688 | ||
Clinical stageb | 8.613 | 0.003 | ||||||||
I–II | 16 | 67.7 | 6 | 83.3 | 10 | 60.0 | 1.042 | 0.307 | ||
III–IV | 53 | 24.7 | 28 | 34.3 | 25 | 13.2 | 7.574 | 0.006 | ||
Recurrence interval (months) | 0.343 | 0.558 | ||||||||
≤30 | 39 | 36.0 | 21 | 37.5 | 18 | 33.3 | 0.126 | 0.723 | ||
>30 | 30 | 33.4 | 13 | 49.0 | 17 | 20.6 | 5.664 | 0.017 | ||
Tumor volume (cm3) | 9.352 | 0.002 | ||||||||
≤26 | 33 | 51.7 | 17 | 42.9 | 16 | 56.3 | 0.023 | 0.881 | ||
>26 | 36 | 18.3 | 17 | 37.6 | 19 | 0.0 | 7.482 | 0.006 |
Abbreviations as in Table 1
aBy log-rank test
bRestage according to the 2002 6th edition TNM staging system of the American Joint Commission on Cancer (AJCC)