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. 2016 Feb 15;13:39. doi: 10.1186/s12974-016-0499-5

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© Hines-Beard et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Treatment with rAAV.EpoR76E increases expression of several antioxidant proteins and increases H-ferritin in the retina. a–c Representative confocal micrographs of H-ferritin immunolabeling in retinas from 3-month controls (a), 8-month-old mice injected with rAAV.eGFP (b), and 8-month-old mice treated with rAAV.EpoR76E (c). d Bar graph quantification of H-ferritin immunofluorescence showing a statistically significant increase in the rAAV.EpoR76E-treated group as compared to rAAV.eGFP-injected mice. e Bar graph of mRNAs with increased expression in 8-month glaucomatous retina as compared to 3-month controls regardless of treatment. f Bar graph of mRNAs with increased expression in retinas from rAAV.EpoR76E-treated 8-month-old mice as compared to age-matched rAAV.eGFP-injected mice