Table 2.

Genes unique to roseoloviruses.

Functiona	Roseolovirus ORF	%S with HHV-6Ab	% I with HHV-6Ac	%S with HHV-7	%I with HHV-7
Roseolovirus specific genes
	U13	93.4	92.5	44.9	35.7
	U15EX1	91.4	86.7	76.4	67.9
	U15EX2	100	95.8	83.3	75
	U15EX3	96.7	91.7	82	75.4
Glycoprotein	U20	95.6	95.6	31.8	22.2
Down-regulation of MHC class I	U21	91	89.8	42.8	31.6
Glycoprotein	U23	94.6	94.1	26.9	20.9
	U24	88.3	82.7	46.2	31.2
	U24A	94.7	91.2	40.3	28.1
	U26	93.8	92.9	60.5	47.4
OX-2 homology, glycoprotein	U85	93.1	91.7	46.9	36.8
IE-A (IE1), transactivator	U90EX1	73.7	68.4	42.8	35.7
	U90EX2	70.3	67.2	67.1	57.1
	U90EX3	76.7	71.5	32.9	25.2
IE-A	U91EX1	67.8	57.1	33.3	25
	U91EX2	69.2	67.9	45.6	40
Spliced envelope glycoprotein; HHV-6 pg82-gp105, HHV-7gp65	U100EX1	78.1	73.4	27.2	19.7
	U100EX2	84.9	81.7	53.8	38.7
	U100EX3	82.9	79.3	40.9	32.7
	U100EX4	96	88	44	40
	U100EX5	88.6	80	34.3	28.6
	U100EX6	91.9	91.9	48.6	37.8
	U100EX7	88.7	83	35.3	27.4
	U100EX8	100	100
	U100EX9	92.8	90.5	35.7	23.8
	U100EX10	83.9	76.5	24	13.3
HHV-6 specific genes
	DR3	87	86.4
	U6	97.1	97.1
	U9	94.2	94.2
Glycoprotein	U22	91.2	89.6
Intercrine cytokine	U83	87.6	85.6
Parvovirus rep homolog	U94	98.4	97.6
HHV-6A gene
	U78
HHV-6B genes
	B3,B4,B5,B6,B7,B8

^aImplied functions of homologous genes or experimental validation.

^bPercentage of amino acid similarity between homologs.

^cPercentage of amino acid identity between homologs.