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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Am J Med Genet A. 2015 Apr 29;0(9):2114–2121. doi: 10.1002/ajmg.a.37138

Figure 2.

Figure 2

Microinjection of ndufb11morpholino (MO) in zebrafish embryos leads to cardiac tissue defects. (A) Bar graph showing cardiac defect phenotype in ndufb11ATG MO 1+ATG MO 2 injected Tg(cmlc2: mRFP) zebrafish embryos at 3 days post fertilization (dpf). Data is represented as mean percentage ± SD (standard deviation) collected over 7 independent experiments and n is number of embryos analyzed. (B–G) Representative images of cardiac defects in zebrafish embryos at 3 dpf. (B,D,E) Non-injected control embryos (NIC) with normal cardiac development and (C,F,G) ndufb11 MO injected embryos displaying defect in cardiac structure. Arrowheads indicate regions with cardiac tissue defect. (H, I) Expression of gata5 transcript in 48 hpf zebrafish embryos. (B,C) 2.5× magnification, (D–G) 5× magnification.