Table 1.

Brain regions selected based on prior knowledge (Gottfried, 2006) about their importance for the human sense of smell. The table lists the number of observations per brain region, the number of patients in whom the respective region showed lesions, and the Shannon information, calculated as Info(BR_i) = - p_0 , i ∙ ln (p_0 , i) - p_1 , i ∙ ln (p_1 , i) , where p_0,i and p_1,i are the observed probabilities of the non-observation or observation, respectively, of a brain lesion obtained as p_0,i = N_damaged / N and p_1,i = 1 − p_0,i.

Region	N	N damaged	Shannon info
Amygdala L	127	11	0.29463346
Amygdala R	127	13	0.33024248
Anterior insula L	127	13	0.33024248
Anterior insula R	127	16	0.37868101
Olfactory bulb L	87	58	0.63651417
Olfactory bulb R	87	57	0.64418578
Entorhinal cortex L	127	57	0.68789898
Entorhinal cortex R	127	40	0.62301241
Frontal cortex L	127	55	0.68416121
Frontal cortex R	127	61	0.69237198
Hypothalamus L	127	18	0.40809566
Hypothalamus R	127	17	0.39365585
Lateral orbitofrontal cortex L	127	59	0.69063407
Lateral orbitofrontal cortex R	127	64	0.69311618
Medial insula L	127	14	0.34700893
Medial insula R	127	12	0.31280067
Medial orbitofrontal cortex L	127	75	0.67665731
Medial orbitofrontal cortex R	127	77	0.67037474
Mesial temporal lobe L	127	33	0.57289213
Mesial temporal lobe R	127	23	0.47306094
Occipital cortex L	127	6	0.19031927
Occipital cortex R	127	11	0.29463346
Pallidum L	127	10	0.27568156
Pallidum R	127	9	0.25587365
Parietal cortex L	127	10	0.27568156
Parietal cortex R	127	13	0.33024248
Perirhinal cortex L	127	58	0.68939147
Perirhinal cortex R	127	40	0.62301241
Piriform cortex L	127	33	0.57289213
Piriform cortex R	127	31	0.55575378
Posterior insula L	127	2	0.08099408
Posterior insula R	127	4	0.13990478
Striatum L	127	2	0.08099408
Striatum R	127	3	0.11181897
Temporal lobe L	127	27	0.5173791
Temporal lobe R	127	29	0.53727061
Thalamus L	127	1	0.04598614
Thalamus R	127	1	0.04598614
Temporal lobe pole L	127	63	0.69311618
Temporal lobe pole R	127	49	0.6668447