Table 2.
Summary of the expression proteomics studies described in section III (see text for details).
| Model | Exposure | Strain/ line | Source | Protein categories, pathways, proteins | Ref. |
|---|---|---|---|---|---|
| human | alcoholic | SFC | α- and β-synuclein, α- and γ enolase, β-neoendorphin-dynorphin, tubulin, pyruvate dehydrogenase, peroxiredoxin 2, heat-shock cognate 71 kDa, tropomyosin 2, tyrosine 3-monooxygenase | (259) | |
| human | alcoholic | SFG, OC | synaptic transmission, vesicle transport, dynamin 1, metabolism, folding, trafficking, signal transduction | (260) | |
| human | cirrhotic | PWM | energy production | (261) | |
| human | cirrhotic | various | thiamine-related biochemical pathways | (262–265) | |
| human | cirrhotic | HIP | glutamine synthetase | (266) | |
| rat | naïve | P/NP | HIP, NAc | signaling pathways, cellular retinoic acid-binding 1, calmodulin-dependent kinase | (267) |
| rat | DID-MSA/CA | iP | NAc, AMY | chaperones, cytoskeleton, intracellular communication, membrane transport, metabolism, energy production, neurotransmission | (268) |
| rat | alcohol injections | P/NP/Wistar | NAc | calcium-calmodulin signaling systems, G-protein signaling systems, synaptic structure, histones | (269) |