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. Author manuscript; available in PMC: 2017 Jan 6.
Published in final edited form as: Neuron. 2015 Dec 10;89(1):147–162. doi: 10.1016/j.neuron.2015.11.023

Figure 6. InsG3680 and R1117X Mutant Mice Display Common and Differential Disruptions of Post-synaptic Signaling Complexes.

Figure 6

(A) Representative blots for proteins detected by specific antibodies in the striatal SPM fraction from wild-type, InsG3680+/+, and R1117X+/+ mice.

(B and C) Quantification of relative levels of proteins as normalized to tubulin protein expression from striatal SPM. (n = 4–6 samples per protein per genotype, each n being pooled tissue from three mice).

(D) Representative blots for proteins detected by specific antibodies in the cortical SPM fraction from wild-type, InsG3680+/+, and R1117X+/+ mice.

(E and F) Quantification of relative levels of proteins as normalized to tubulin protein expression from cortex SPM. (n = 4–11 samples per protein per genotype, each n being pooled tissue from two mice).

In (B), (C), (E), and (F), data are presented as mean ± SEM. *p < 0.05, **p < 0.01, **p < 0.001; one sample t test.