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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Neurobiol Learn Mem. 2016 Jan 9;128:103–109. doi: 10.1016/j.nlm.2016.01.001

Figure 1. Inhibiting CaMKII activity in vitro can reverse retrieval-induced changes in proteasome activity in the amygdala.

Figure 1

(A) Animals were trained to contextual fear conditioning and exposed to the training context the following day. Amygdala crude synaptosomal membrane fractions were then collected 1.5-hrs later (n = 8 per group). (B) Amygdala proteasome activity was increased following exposure to the training context during retrieval. (C) There were no differences between groups in the presence of the CaMKII inhibitor AIP indicating that (D) inhibiting CaMKII in vitro reversed the retrieval-induced increases in proteasome activity in the amygdala. Number inside bar denotes group size for that specific assay. * P < 0.05 from No React on independent-samples t-test.