Table 2. Summary of selected publications of patients with MPM.

Study	Type	N	Summary findings
Yan (29)	International multi-center retrospective review	405	Factor associated with best OS were CCR 0-1, histopathology
Alexander (31)	United States, 3 centers retrospective review	211	Factors associated with best OS were CCR 0-1, histopathology, cisplatin versus mitomycin HIPEC
Miura (32)	SEER database review [1973-2010]	1,591	OS increased over time in patients undergoing operation; over 60% of MPM patients received no surgical therapy
Helm (13)	Meta-analysis 20 CRS and HIPEC publications	1,047	Median age: 51 years; 59% female gender; median PCI: 19; CCR 0-1: 67%

MPM, malignant peritoneal mesothelioma; OS, overall survival; PCI, peritoneal cancer index; CCR, completeness of cytoreduction.