Table 4. Outcomes of palliative HIPEC for malignant ascites.
Year | Author | N | Tumor | Agent(s) | Technique | Response (%) | Median survival [range] |
---|---|---|---|---|---|---|---|
2006 | Garofalo | 14 | Varied | Cisplatin and doxorubicin or mitomycin | Laparoscopic | 100 | 203 days [21-667] |
2008 | Facchiano | 5 | Gastric | Mitomycin and cisplatin | Laparoscopic | 100 | 89 days [33-144] |
2008 | Patriti | 1 | Mesothelioma | Cisplatin and doxorubicin | Laparoscopic | 100 | 6 months |
2009 | Valle | 52 | Varied | Cisplatin and doxorubicin or mitomycin | Laparoscopic | 98 | 98 days [21-796] |
2010 | Ba | 16 | Gastric | 5-fluorouracil and oxaliplatin | Laparoscopic | 88 | 5 months [2-9] |
2013 | Ba | 62 | Ovarian | Cisplatin and doxorubicin | Laparoscopic | 93 | 8 months [2-20] |
Gastrointestinal | Mitomycin | B-ultrasound guided | 94 | 9 months [2-30] | |||
2014 | Randle | 299 | Varied | Mitomycin, carboplatin, oxaliplatin, cisplatin, | Open | 93 | 5.3 months* |
*, incomplete cytoreduction, non-low grade appendiceal cancers. HIPEC, hyperthemic intraperitoneal chemoperfusion.