Figure 4. Curcumin and ALA combined increases DHA and DHA-synthesis-related enzymes in the liver.
ALA alone increase DHA in the liver, which is further elevated when ALA is combined with CUR at both 250 and 500 ppm doses, whereas CUR alone did not elevate liver DHA content (A). FADS2 was significantly increased in both ALA+CUR groups compared to other groups (B). Elov2 was higher in all CUR groups compared to other groups (C). Representative bands for FADS2 and Elov2 (D). FADS2: delta 6 desaturase, Elov2: elongase, CTL: control, ALA: α-linolenic acid, CUR: curcumin. *compared with control (p<0.05); # compared with indicated p<0.05 (n=5–6).