Table IV.
Baseline characteristics of REGARDS participants whose reduced eGFRcr was confirmed versus not confirmed using eGFRcys stratified by age
| Parameter | < 65 years | 65 to 79 years | ≥ 80 years | |||
|---|---|---|---|---|---|---|
| Reduced eGFRcr confirmed using eGFRcys | Reduced eGFRcr not confirmed using eGFRcys | Reduced eGFRcr confirmed using eGFRcys | Reduced eGFRcr not confirmed using eGFRcys | Reduced eGFRcr confirmed using eGFRcys | Reduced eGFRcr not confirmed using eGFRcys | |
| Number of participants (%)a | 458 (76.5) | 141 (23.5) | 1,547 (85.7) | 258 (14.3) | 606 (92.5) | 49 (7.5) |
| Age, mean (SD) [years] | 59.3 (4.0) | 59.2 (4.3) | 72.4 (4.2) | 72.0 (4.11) | 83.6 (3.2) | 83.3 (3.0) |
| Men, n (%) | 189 (41.3) | 73 (51.8) | 677 (43.8) | 122 (47.3) | 295 (48.7) | 25 (51.0) |
| Black, n (%) | 277 (60.5) | 63 (44.7) | 616 (39.8) | 108 (41.9) | 199 (32.8) | 19 (38.8) |
| Region of residence, n (%): | ||||||
| Stroke belt (buckle states) | 110 (24.0) | 26 (18.4) | 340 (22.0) | 42 (16.3) | 122 (20.1) | 8 (16.3) |
| Stroke belt (non-buckle states) | 166 (36.3) | 44 (31.2) | 525 (33.9) | 78 (30.2) | 175 (28.9) | 13 (26.5) |
| Other contiguous US states | 182 (39.7) | 71 (50.4) | 682 (44.1) | 138 (53.5) | 309 (51.0) | 28 (57.2) |
| Less than high school, n (%) | 68 (14.9) | 9 (6.4) | 316 (20.4) | 36 (14.0) | 136 (22.6) | 9 (18.4) |
| No physical activity, n (%) | 215 (47.4) | 41 (29.5) | 727 (48.2) | 70 (27.7) | 317 (53.6) | 15 (30.6) |
| Current smoking, n (%) | 87 (19.0) | 13 (9.3) | 181 (11.7) | 13 (5.0) | 25 (4.1) | 1 (2.1) |
| History of CHD, n (%) | 136 (30.4) | 26 (18.8) | 543 (35.9) | 50 (19.9) | 201 (34.0) | 9 (18.4) |
| History of stroke, n (%) | 67 (14.8) | 5 (3.6) | 222 (14.4) | 17 (6.6) | 71 (11.8) | 7 (14.3) |
| Diabetes, n (%) | 234 (51.3) | 30 (21.4) | 564 (36.6) | 55 (21.5) | 165 (27.2) | 4 (8.2) |
| High waist circumference, n (%) | 316 (70.2) | 64 (46.0) | 918 (59.6) | 100 (39.1) | 270 (44.8) | 18 (36.7) |
| Body mass index, n (%) [kg/m2]: | ||||||
| < 18.5 | 1 (0.2) | 1 (0.7) | 17 (1.1) | 4 (1.6) | 16 (2.7) | 1 (2.0) |
| 18.5 to < 25.0 | 55 (12.4) | 18 (13.0) | 331 (21.5) | 62 (24.2) | 194 (32.2) | 21 (42.8) |
| 25.0 to < 30.0 | 115 (25.9) | 56 (40.6) | 550 (35.7) | 121 (47.3) | 246 (40.9) | 21 (42.8) |
| ≥ 30.0 | 273 (61.5) | 63 (45.7) | 643 (41.7) | 69 (16.9) | 146 (24.2) | 6 (4.4) |
| Taking statins, n (%) | 213 (46.5) | 54 (38.3) | 734 (47.5) | 116 (45.0) | 254 (41.9) | 11 (22.5) |
CHD – coronary heart disease, eGFR – estimated glomerular filtration rate, REGARDS – REasons for Geographic And Racial Differences in Stroke, SD – standard deviation, US – United States.
a
Percentage within age group. Reduced eGFRcr confirmed using eGFRcys was defined as eGFRcr and eGFRcys < 60 ml/min/1.73 m2. Reduced eGFRcr not confirmed using eGFRcys was defined as eGFRcr < 60 ml/min/1.73 m2 and eGFRcys ≥ 60 ml/min/1.73 m2. Equations for eGFRcr and eGFRcys are shown in Table I.